Creatinine clearance calculation with urine creatinine 90 mg/dL, urine volume 1500 mL/day, serum creatinine 0.90 mg/dL, and total body surface 1.73 m^2 yields which value (mL/min)?

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Multiple Choice

Creatinine clearance calculation with urine creatinine 90 mg/dL, urine volume 1500 mL/day, serum creatinine 0.90 mg/dL, and total body surface 1.73 m^2 yields which value (mL/min)?

Explanation:
Creatinine clearance estimates GFR by comparing how much creatinine is excreted in urine to how much is present in the blood, using the formula CrCl = (UCr × V) / Scr, with UCr and Scr in mg/dL and V in mL/min. Here, urine volume is 1500 mL/day, so convert to per minute: 1500 mL/day ÷ 1440 min/day ≈ 1.0417 mL/min. The ratio UCr/Scr is 90 mg/dL divided by 0.90 mg/dL = 100. Multiply: 100 × 1.0417 ≈ 104 mL/min. The total body surface area is 1.73 m^2, so normalizing to 1.73 m^2 leaves the value unchanged. Therefore, the creatinine clearance is about 104 mL/min.

Creatinine clearance estimates GFR by comparing how much creatinine is excreted in urine to how much is present in the blood, using the formula CrCl = (UCr × V) / Scr, with UCr and Scr in mg/dL and V in mL/min. Here, urine volume is 1500 mL/day, so convert to per minute: 1500 mL/day ÷ 1440 min/day ≈ 1.0417 mL/min. The ratio UCr/Scr is 90 mg/dL divided by 0.90 mg/dL = 100. Multiply: 100 × 1.0417 ≈ 104 mL/min. The total body surface area is 1.73 m^2, so normalizing to 1.73 m^2 leaves the value unchanged. Therefore, the creatinine clearance is about 104 mL/min.

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